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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T64603 | Akt Antibody #9272R | ||
Akt Antibody #9272R is a useful organic compound for research related to life sciences and the catalog number is T64603. | |||
T64583 | Phospho-Akt (Ser473) Antibody #9271R | ||
Phospho-Akt (Ser473) Antibody #9271R is a useful organic compound for research related to life sciences and the catalog number is T64583. | |||
T76795 | Xentuzumab | BI 836845 | Akt , IGF-1R |
Xentuzumab (BI836845) is a recombinant monoclonal antibody to humanised IGF ligand that inhibits IGF1 and IGF2 growth-promoting signalling and inhibits AKT activation for the study of solid tumours. | |||
T76727 | Teprotumumab | R 1507,HZN 001 | TSH Receptor , IGF-1R |
Teprotumumab is a human monoclonal antibody that blocks the IGF-1 receptor (IGF-1R). Teprotumumab binds to the extracellular α-subunit domain ligand of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Te... | |||
T76796 | Patritumab | U3-1287,AMG-888 | ERK , EGFR , Akt , HER |
Patritumab (U3-1287) is an anti-HER3 monoclonal antibody with potential antitumor activity and inhibits phosphorylation of EGFR, HER2, HER3, ERK, and AKT.Patritumab promotes apoptosis and inhibits proliferation in non-sm... | |||
T76736 | Abituzumab | ||
Abituzumab (DI17E6), a humanized IgG2-type anti-integrin αV monoclonal antibody, notably decreases phosphorylation of FAK, Akt, and ERK. Its application is significant in cancer research, with a particular emphasis on pr... | |||
T76723 | Tilvestamab | ||
Tilvestamab (BGB149), a humanized anti-AXL antibody, effectively blocks AXL-mediated cell signaling, significantly reduces Gas6-induced AXL activation, and inhibits downstream AKT phosphorylation in 786-0-Luc RCC cells. ... | |||
T76800 | Dalotuzumab | ||
Dalotuzumab (MK-0646) is a humanized recombinant monoclonal antibody (IgG1 type) that targets IGF-1R, inhibiting tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation mediated by IGF-1 and IGF-2. ... |